At COP26, an initial group of 15 leading nations signed a Global Memorandum of Understanding (MOU) for Zero-Emission Medium- and Heavy-Duty Vehicles, establishing a clearly defined goal of 30 percent zero-emission commercial vehicle sales by 2030 and 100 percent sales by 2040. Supported by over 40 subnational government and industry endorsements, this Global MOU is the centerpiece of a landmark Global Agreement on Zero-Emission Trucks and Buses establishing a clear pathway for the commercial on-road transportation sector to reach net zero carbon by 2050 in alignment with the Paris Agreement.